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Detect sepsis before it becomes irreversible

48–72 hours earlier than conventional models

Prescient’s Sepsis Early Warning identifies patients on a deterioration trajectory before lactate rises, before MEWS triggers, and well before Epic’s native model fires — enabling intervention when outcomes are still modifiable.

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Why This Matters

Sepsis is not a sudden event. It is a trajectory failure.

  • Most systems detect sepsis too late in the curve
  • Alerting is driven by threshold breaches, not trajectory shifts
  • By the time alerts fire, clinical options are already constrained

Result

Delayed intervention → higher mortality → higher cost → avoidable ICU utilization

What Prescient Does Differently

Trajectory-Based Detection — Not Threshold-Based Alerting

Instead of waiting for abnormal values, Prescient models how a patient is trending toward sepsis.

Key signals include:

  • Subclinical vitals drift
  • Lab progression patterns
  • Clinical note signals (NLP-derived)
  • Treatment-response deviation
  • Prior utilization context

How It Works

Continuous Risk Scoring Across the Care Continuum

Every 15 minutes, the system

Ingests real-time clinical + historical data

Computes trajectory-based risk scores

Updates patient ranking across ED and inpatient settings

Pushes prioritized alerts to clinicians

What Clinicians See

Not another alert. A prioritized decision signal.

Example output:

CRITICAL · SEPSIS RISK

74F · ED Bay 3

  • Lactate: 3.2
  • Temp: 38.9°C
  • Trajectory indicates sepsis onset in 48–72h

Composite Risk Score: 97

Daily Priority Patient List

Instead of scanning charts, teams receive:

  • Ranked list of highest-risk patients
  • Clear clinical rationale
  • Time-to-deterioration estimate

Clinical Impact

Earlier antibiotic initiation

Reduced septic shock progression

Lower ICU admissions

Improved SEP-1 compliance performance

Why It Outperforms Epic Esm

Capability

  • Detection logic
  • Timing
  • Miss rate
  • Workflow

Epic ESM

  • Threshold-based
  • Late-stage
  • High
  • Reactive alerts

Prescient

  • Trajectory-based
  • 48–72h earlier
  • Reduced via multi-signal modeling
  • Proactive prioritization

Integration

  • Read-only HL7/FHIR integration with Epic
  • No workflow disruption
  • Alerts delivered within existing clinical workflows

Pilot Approach

  • 90–180 day pilot using historical Epic data
  • Back-tested detection vs. actual outcomes
  • Clear success metrics defined upfront

See sepsis detection before the curve turns

Request a clinical demo and evaluate performance against your own data.